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Lipase inhibitors can be found naturally in plants and can also be produced as pharmaceutical drugs.Some lipase inhibitors have been identified in Panax ginseng. [5] [6] Some active compounds with chalcone scaffold found in Glycyrrhiza glabra, Cassia mimosoides, Glycyrrhiza uralensis, Boesenbergia rotunda, apples and Morus alba also had strong effect against lipase.
Lipase inhibitors belong to a drug class that is used as an antiobesity agent. Their mode of action is to inhibit gastric and pancreatic lipases, enzymes that play an important role in the digestion of dietary fat. [2] Lipase inhibitors are classified in the ATC-classification system as A08AB (peripherally acting antiobesity products). [3]
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Research hints that medications like Zepbound and Wegovy could provide new ways to treat opioid and alcohol abuse.
Nora D. Volkow, MD, is director of the National Institute on Drug Abuse (NIDA) at the National Institutes of Health. Ozempic and other similar weight-loss drugs (collectively known as GLP-1 ...
Weight loss drugs have been developed since the early twentieth century, and many have been banned or withdrawn from the market due to adverse effects, including deaths; other drugs proved ineffective. Although many earlier drugs were stimulants such as amphetamines, in the early 2020s, GLP-1 receptor agonists became popular for weight loss.
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