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Pimobendan is indicated for the management of the signs of mild, moderate, or severe congestive heart failure in dogs due to clinical myxomatous mitral valve disease (MMVD) or dilated cardiomyopathy (DCM); [1] [7] and for use with concurrent therapy for congestive heart failure (e.g.,furosemide, etc.) as appropriate on a case-by-case basis. [1]
Dogs with overt disease may also have episodic weakness and exercise intolerance, but syncope is the predominant manifestation. The third form, which is recognized much less frequently, is characterized by myocardial systolic dysfunction. This may result in left-sided, right-sided, or bi-ventricular congestive heart failure. It is not known if ...
A major veterinary study, called the QUEST study (QUality of life and Extension of Survival Time), published in September 2008 found that dogs with congestive heart failure receiving pimobendan plus furosemide had significantly better survival outcomes than those receiving benazepril (an ACE inhibitor) plus furosemide. [26]
It is a congenital heart disease in dogs. There usually are no signs in dogs except for a heart murmur. However, a large defect can result in heart failure or in pulmonary hypertension leading to a right-to-left shunt. [49] Atrial septal defect* is a hole in the division between the heart atria (upper chambers of the heart). It is an uncommon ...
The minimum lethal dose in dogs is over 5 mg/m 2; dogs have tolerated getting ten times the standard dose. [9] [33] Signs of overdose include panting, trembling, vomiting, and diarrhea, as well as increased blood levels of creatine kinase, aspartate transaminase, and alanine transaminase. Dogs who received atipamezole without first receiving ...
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