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  2. Histamine intolerance - Wikipedia

    en.wikipedia.org/wiki/Histamine_intolerance

    The manifestations of histamine intolerance, or, adverse reactions to ingested histamine, are not confined to the gastrointestinal system, and are usually systemic, affecting the entire body; still, these symptoms are often sporadic and non-specific: [5] [6] [7] symptoms attributed to histamine intolerance are wide-ranging and may affect various physiological systems, including the skin ...

  3. H1 antagonist - Wikipedia

    en.wikipedia.org/wiki/H1_antagonist

    H 1 antagonists, also called H 1 blockers, are a class of medications that block the action of histamine at the H 1 receptor, helping to relieve allergic reactions.Agents where the main therapeutic effect is mediated by negative modulation of histamine receptors are termed antihistamines; other agents may have antihistaminergic action but are not true antihistamines.

  4. Clemastine - Wikipedia

    en.wikipedia.org/wiki/Clemastine

    Clemastine, also known as meclastin, is a first-generation H1 histamine antagonist (antihistamine) with anticholinergic properties (drying) and sedative side effects. [1] Like all first-generation antihistamines, it is sedating.

  5. H3 receptor antagonist - Wikipedia

    en.wikipedia.org/wiki/H3_receptor_antagonist

    An H 3 receptor antagonist is a type of antihistaminic drug used to block the action of histamine at H 3 receptors.. Unlike the H 1 and H 2 receptors which have primarily peripheral actions, but cause sedation if they are blocked in the brain, H 3 receptors are primarily found in the brain and are inhibitory autoreceptors located on histaminergic nerve terminals, which modulate the release of ...

  6. Cetirizine - Wikipedia

    en.wikipedia.org/wiki/Cetirizine

    Among second-generation antihistamines, cetirizine is more likely than fexofenadine and loratadine to cause drowsiness. [7] Use in pregnancy appears safe, but use during breastfeeding is not recommended. [8] The medication works by blocking histamine H 1 receptors, mostly outside the brain. [6] Cetirizine can be used for paediatric patients.

  7. H2 receptor antagonist - Wikipedia

    en.wikipedia.org/wiki/H2_receptor_antagonist

    Cimetidine was the prototypical histamine H 2 receptor antagonist from which later drugs were developed. Cimetidine was the culmination of a project at Smith, Kline & French (SK&F; now GlaxoSmithKline) by James W. Black, C. Robin Ganellin, and others to develop a histamine receptor antagonist that would suppress stomach acid secretion.