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Central nervous system fatigue, or central fatigue, is a form of fatigue that is associated with changes in the synaptic concentration of neurotransmitters within the central nervous system (CNS; including the brain and spinal cord) which affects exercise performance and muscle function and cannot be explained by peripheral factors that affect muscle function.
“Fatigue that lasts for six months or more is usually called chronic fatigue syndrome, or myalgic encephalitis [ME]. This is a complex, poorly understood, disabling illness that is often ...
The Canadian Consensus Criteria require "post exertional malaise and/or [post exertional] fatigue" instead. [20] [21] [22] [18] [23] On the other hand, the older Oxford Criteria lack any mention of PEM, [24] and the Fukuda Criteria consider it optional. Depending on the definition of ME/CFS used, PEM is present in 60 to 100% of ME/CFS patients. [6]
A few other major signs to look out for include extreme fatigue, headaches, fever, a butterfly-shaped rash across the cheeks and nose, hair loss, and Raynaud’s phenomenon (a condition in which ...
In a person who does not tolerate exercise well, physical activity may cause unusual breathlessness , muscle pain , tachypnoea (abnormally rapid breathing), inappropriate rapid heart rate or tachycardia (having a faster heart rate than normal), increasing muscle weakness or muscle fatigue; or exercise might result in severe headache, nausea ...
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