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TRANSFAC (TRANScription FACtor database) is a manually curated database of eukaryotic transcription factors, their genomic binding sites and DNA binding profiles. The contents of the database can be used to predict potential transcription factor binding sites .
The JASPAR CORE database contains a curated, non-redundant set of profiles, derived from published collections of experimentally defined transcription factor binding sites for eukaryotes. database: website [11] [12] MethMotif An integrative cell-specific database of transcription factor binding motifs coupled with DNA methylation profiles ...
TcoF-DB: Database of transcription co-factors and transcription factor interactions [98] TFcheckpoint: database of human, mouse and rat TF candidates; transcriptionfactor.org (now commercial, selling reagents) MethMotif.org: An integrative cell-specific database of transcription factor binding motifs coupled with DNA methylation profiles. [99]
Transcription factors (TFs) are proteins that bind DNA and thus regulate the trasncription process. The binding is sequence-specific. A sequence motif [5] is a model that describes the common pattern of the DNA binding sites [6] that a particular TF prefers to bind. One of the possible representations of the model is the Position-Weight Matrix ...
The Open Regulatory Annotation Database (also known as ORegAnno) is designed to promote community-based curation of regulatory information. Specifically, the database contains information about regulatory regions, transcription factor binding sites, regulatory variants, and haplotypes.
Gene prediction is one of the key steps in genome annotation, following sequence assembly, the filtering of non-coding regions and repeat masking. [3] Gene prediction is closely related to the so-called 'target search problem' investigating how DNA-binding proteins (transcription factors) locate specific binding sites within the genome.
This list of manually curated human transcription factors is taken from Lambert, Jolma, Campitelli et al. [1] It was assembled by manual curation. More detailed information is found in the manuscript and the web site accompanying the paper ( Human Transcription Factors )
AnimalTFDB; Content; Description: animal transcription factor database.: Contact; Research center: Huazhong University of Science and Technology: Laboratory: Hubei Bioinformatics & Molecular Imaging Key Laboratory