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A dosage of two to six 100 μg/day transdermal estradiol patches can achieve mean levels of estradiol in the area of 200 to 400 pg/mL and can be used as a form of high-dose estrogen therapy, for instance to suppress testosterone levels in the treatment of prostate cancer in men and in feminizing hormone therapy for transgender women.
Estradiol is an estrogen, or an agonist of the nuclear estrogen receptors (ERs), the estrogen receptor alpha (ERα) and the estrogen receptor beta (ERβ). [1] [2] [6] In one study, the EC 50 Tooltip half-maximal effective concentration value of estradiol for the human ERα was 50 pM (0.05 nM) and for the human ERβ was 200 pM (0.2 nM).
Alfatradiol, also known as 17α-estradiol and sold under the brand names Avicis, Avixis, Ell-Cranell Alpha, and Pantostin, is a weak estrogen and 5α-reductase inhibitor medication which is used topically in the treatment of pattern hair loss (androgenic alopecia or pattern baldness) in men and women.
Men, especially those with low T, can get hot flashes, too. Low levels of testosterone and decreased estrogen can both lead to hot flashes because they both stimulate cortisol release.
Experts call vaginal estrogen "the holy grail" for its effectiveness in improving vulvar or vaginal itching and burning, painful sex and recurring UTIs.
This is the same as estrogen, and it’s used as a medication to manage and treat symptoms of menopause. Estradiol is the most common form of the estrogen hormone for hormone replacement therapy ...
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