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  2. Macrogol - Wikipedia

    en.wikipedia.org/wiki/Macrogol

    Macrogol 4000, pharmaceutical quality. Macrogol 3350, often in combination with electrolytes, is used for short-term relief of constipation as well as for long-term use in constipation of various causes, including in multiple sclerosis and Parkinson's disease patients (an often-overlooked non-motor symptom) as well as constipation caused by pharmaceutical drugs such as opioids and ...

  3. With laxatives in high demand, doctors warn not to take them ...

    www.aol.com/news/laxatives-high-demand-doctors...

    The median age in the U.S. has also reached a record high (nearly 39 years), and people have become more sedentary, are eating less healthy diets and are taking more medications than ever, all of ...

  4. Laxative - Wikipedia

    en.wikipedia.org/wiki/Laxative

    Prolonged use of stimulant laxatives can create drug dependence by damaging the colon's haustral folds, making users less able to move feces through their colon on their own. A study of patients with chronic constipation found that 28% of chronic stimulant laxative users lost haustral folds over the course of one year, while none of the control ...

  5. Are laxatives for weight loss safe? - AOL

    www.aol.com/laxatives-weight-loss-safe-153000701...

    Osmotic laxatives: Products such as Miralax (polyethylene glycol) pull water from other parts of the body and into the colon. This extra water adds volume and pressure, which can make it easier to ...

  6. 4 of the Top Prescription Weight Loss Pills & How They Work - AOL

    www.aol.com/4-top-prescription-weight-loss...

    Blocked fat absorption. Certain weight loss drugs inhibit the absorption of dietary fats by blocking the digestive enzymes that break down fat. This reduces the number of calories you absorb overall.

  7. First pass effect - Wikipedia

    en.wikipedia.org/wiki/First_pass_effect

    First-pass metabolism may occur in the liver (for propranolol, lidocaine, clomethiazole, and nitroglycerin) or in the gut (for benzylpenicillin and insulin). [4] The four primary systems that affect the first pass effect of a drug are the enzymes of the gastrointestinal lumen, [5] gastrointestinal wall enzymes, [6] [7] [8] bacterial enzymes [5] and hepatic enzymes.

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