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  2. Donepezil - Wikipedia

    en.wikipedia.org/wiki/Donepezil

    Donepezil has been tested in other cognitive disorders, including Lewy body dementia, [33] and vascular dementia, [34] but it is not currently approved for these indications. Donepezil has also been found to improve sleep apnea in people with Alzheimer's. [35] It also improves gait in people with mild Alzheimer's. [36]

  3. Dementia with Lewy bodies - Wikipedia

    en.wikipedia.org/wiki/Dementia_with_Lewy_bodies

    People with Lewy body dementias who take neuroleptics are at risk for neuroleptic malignant syndrome, a life-threatening illness. [51] There is no evidence to support the use of antipsychotics to treat the Lewy body dementias, [10] and they carry the additional risk of stroke when used in the elderly with dementia. [86]

  4. The first treatment was a cholinesterase inhibitor called donepezil, ... “I’ve seen them help many of my Lewy body patients and in some cases they seem even more helpful than in Alzheimer’s ...

  5. Category:Lewy body dementia - Wikipedia

    en.wikipedia.org/wiki/Category:Lewy_body_dementia

    Pages in category "Lewy body dementia" ... Dementia with Lewy Bodies Consortium; Donepezil; K. Kenji Kosaka (psychiatrist) L. Lewy body; Lewy Body Dementia Association;

  6. Lewy body dementia - Wikipedia

    en.wikipedia.org/wiki/Lewy_body_dementia

    Lewy body dementia (LBD) is an umbrella term for two similar and common subtypes of dementia: [1] dementia with Lewy bodies (DLB) and Parkinson's disease dementia (PDD).

  7. Cholinesterase inhibitor - Wikipedia

    en.wikipedia.org/wiki/Cholinesterase_inhibitor

    Paraoxon and rivastigmine are both acetylcholinesterase inhibitors and butyrylcholinesterase inhibitors. [14] [11] [7]In 2015, the United States Food and Drug Administration's Adverse Event Reporting System database compared rivastigmine to the other ChEI drugs donepezil and galantamine found that rivastigmine was associated with a higher frequency of reports of death as an adverse event.

  8. Acetylcholinesterase inhibitor - Wikipedia

    en.wikipedia.org/wiki/Acetylcholinesterase_inhibitor

    To treat Alzheimer's disease, the Lewy body dementias and Parkinson's disease. In these neurodegenerative conditions AChEIs are primarily used to treat the cognitive (memory and learning deficits mostly) symptoms of dementia. These symptoms are attenuated due to the role of acetylcholine in cognition in the CNS. There is some evidence to ...

  9. Lewy body - Wikipedia

    en.wikipedia.org/wiki/Lewy_body

    A Lewy body is composed of the protein α-synuclein associated with other proteins, such as ubiquitin, [9] neurofilament protein, and alpha B crystallin. Tau proteins may also be present, and Lewy bodies may occasionally be surrounded by neurofibrillary tangles .