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CA 15-3, for Carcinoma Antigen 15-3, is a tumor marker for many types of cancer, most notably breast cancer. [1] [2] [3]It is derived from MUC1. [4] CA 15-3 and associated CA 27-29 are different epitopes on the same protein antigen product of the breast cancer-associated MUC1 gene.
A tumor marker is a biomarker that can be used to indicate the presence of cancer or the behavior of cancers ... CA15-3: breast cancer [9] CA27.29: breast cancer [10 ...
CA 27.29 (aka BR 27.29) and CA 15-3 measure different epitopes of the same protein antigen product of the MUC1 gene seen in breast cancer. CA 27.29 has enhanced sensitivity and specificity compared to CA 15-3 and is elevated in 30% of patients with low-stage disease and 60 to 70% of patients with advanced-stage breast cancer.
Pages in category "Tumor markers" The following 45 pages are in this category, out of 45 total. ... CA 15-3; CA 27-29; CA 242 (tumor marker) CA19-9; Calcitonin;
Recent studies have shown changes of MUC-1 family antigences (CA 15-3, CA 27.29 and MCA) in saliva in breast cancer patients. Downregulated MUC1 was associated with HER2(+), high Ki-67 and G II-III. It showed a statistically significant increase in the cytokines VEGF, IL-1β, IL-2, IL-4, IL-10, and IL-18 against the background of reduced ...
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n/a Ensembl ENSG00000181143 n/a UniProt Q8WXI7 n/a RefSeq (mRNA) NM_024690 NM_001401501 n/a RefSeq (protein) NP_078966 n/a Location (UCSC) Chr 19: 8.85 – 8.98 Mb n/a PubMed search n/a Wikidata View/Edit Human Mucin-16 (MUC-16) also known as Ovarian cancer-related tumor marker CA125 is a protein that in humans is encoded by the MUC16 gene. MUC-16 is a member of the mucin family glycoproteins ...
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