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  2. Salicylate poisoning - Wikipedia

    en.wikipedia.org/wiki/Salicylate_poisoning

    Salicylate poisoning, also known as aspirin poisoning, is the acute or chronic poisoning with a salicylate such as aspirin. [1] The classic symptoms are ringing in the ears, nausea, abdominal pain, and a fast breathing rate. [1] Early on, these may be subtle, while larger doses may result in fever.

  3. Aspirin - Wikipedia

    en.wikipedia.org/wiki/Aspirin

    Aspirin is not recommended in the last part of pregnancy. [11] It is not generally recommended in children with infections because of the risk of Reye syndrome. [11] High doses may result in ringing in the ears. [11] A precursor to aspirin found in the bark of the willow tree (genus Salix) has been used for its health effects for at least 2,400 ...

  4. Daily low-dose aspirin has its benefits — and risks. Here's ...

    www.aol.com/lifestyle/aspirin-every-day-why-not...

    More recently, a study of more than 100,000 people published in early August found that those who led less healthy lifestyles — they smoked, drank more alcohol and didn’t have much physical ...

  5. Reye syndrome - Wikipedia

    en.wikipedia.org/wiki/Reye_syndrome

    Prevention is typically by avoiding the use of aspirin in children. [1] When aspirin was withdrawn for use in children in the US and UK in the 1980s, a decrease of more than 90% in rates of Reye syndrome was observed. [2] Early diagnosis of the syndrome improves outcomes. [1] Treatment is supportive; [1] mannitol may be used to help with the ...

  6. Aspirin-exacerbated respiratory disease - Wikipedia

    en.wikipedia.org/wiki/Aspirin-exacerbated...

    The first adverse reactions to aspirin were described in 1902 in Germany, only four years after aspirin's commercial introduction. [53] The first published report of an aspirin-induced asthma attack was in 1911. [54] Initial reports on the linkage between asthma, aspirin, and nasal polyposis were made by Georges-Fernand Widal et al. in 1922. [55]

  7. Mechanism of action of aspirin - Wikipedia

    en.wikipedia.org/wiki/Mechanism_of_action_of_aspirin

    It does so by acetylating the hydroxyl of a serine residue at the 530 amino acid position. [6] Normally COX produces prostaglandins, most of which are pro-inflammatory, and thromboxanes, which promote clotting. Aspirin-modified COX-2 produces 15-epi-lipoxins, which act to resolve inflammatory responses similar to other lipoxins. [7]

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  9. Drug rash with eosinophilia and systemic symptoms - Wikipedia

    en.wikipedia.org/wiki/Drug_rash_with_eosinophil...

    The symptoms of DRESS syndrome usually begin 2 to 6 weeks but uncommonly up to 8–16 weeks after exposure to an offending drug. Symptoms generally include fever, an often itchy rash which may be morbilliform or consist mainly of macules or plaques, facial edema (i.e. swelling, which is a hallmark of the disease), enlarged and sometimes painful lymph nodes, and other symptoms due to ...

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