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M2-PK, as measured in feces, is a potential tumor marker for colorectal cancer. When measured in feces with a cutoff value of 4 U/ml, its sensitivity has been estimated to be 85% (with a 95% confidence interval of 65 to 96%) for colon cancer and 56% (confidence interval 41–74%) for rectal cancer. [1] Its specificity is 95%. [2]
A tumor marker is a biomarker that can be used to indicate the presence of cancer or the behavior of cancers (measure progression or response to therapy). They can be found in bodily fluids or tissue. Markers can help with assessing prognosis, surveilling patients after surgical removal of tumors, and even predicting drug-response and monitor ...
A biomarker may be used to see how well the body responds to a treatment for a disease or condition. Also called molecular marker and signature molecule." [18] In cancer research and medicine, biomarkers are used in three primary ways: [19] To help diagnose conditions, as in the case of identifying early stage cancers (diagnostic)
That tumour markers in your blood work are no good for detecting Some cancers, notably bowel cancer. Schedule a routine colonoscopy and listen to your body for symptoms.
The gold standard of early detection of colon polyp/cancer is the invasive colonoscopy, but with high expense about $557, while tumor marker M2-PK Test expense only about $15-$25. The invasive colonoscopy makes acceptance of it low among patients, so relatively cheap non-invasive M2-PK Test is a good choice for detection early polyp/cancer.
Left-sided tumors generally tend to have higher CEA levels than right-sided tumors. [16] Tumors causing bowel obstruction produce higher CEA levels. [16] Aneuploid tumors produce more CEA than diploid tumors. [17] Liver dysfunction increases CEA levels as the liver is the primary site of CEA metabolism. [3]
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