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The risks of using high-strength minoxidil include an increased likelihood of side effects. When using it as a topical solution, side effects of minoxidil may include: Skin irritation
Side effects from topical and oral minoxidil can differ. When taken orally, minoxidil may cause side effects such as fluid retention, elevated heart rate and increased body hair growth.
Minoxidil (brand name Rogaine®) is a non-prescription topical medication that promotes hair growth and regrowth by restarting the growth phase in dormant hair follicles.
Minoxidil is a medication used for the treatment of high blood pressure and pattern hair loss. [5] [6] [7] It is an antihypertensive and a vasodilator. [10] It is available as a generic medication by prescription in oral tablet form and over-the-counter as a topical liquid or foam. [8] [9] [11] [12]
Finasteride and minoxidil are usually first line therapy for its treatment. Other options include topical or systemic spironolactone or flutamide, although they have a high incidence of feminising side effects and are better tolerated in female androgenic hair loss.
Minoxidil sulfate is formed from minoxidil via sulfotransferase enzymes, with the predominant enzyme responsible, at least in hair follicles, being SULT1A1. [ 1 ] [ 2 ] Minoxidil sulfate acts as a potassium channel opener , among other actions, and has vasodilating , hypotensive , and trichogenic or hypertrichotic (hair growth-promoting) effects.