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A cold sore [a] is a type of herpes infection caused by the herpes simplex virus that affects primarily the lip. [1] Symptoms typically include a burning pain followed by small blisters or sores . [ 1 ]
What are cold sores? Cold sores, also known as fever blisters, can appear on your mouth or lip and are usually caused by oral herpes or herpes simplex virus type 1 (HSV-1). “It’s extremely ...
Herpes infections are categorized by the area of the body that is infected. The two major types of herpes are oral herpes and genital herpes, though other forms also exist. Oral herpes involves the face or mouth. It may result in small blisters in groups, often called cold sores or fever blisters, or may just cause a sore throat.
In 2009, acyclovir in combination with hydrocortisone cream, marketed as Xerese, was approved in the United States for the early treatment of recurrent herpes labialis (cold sores) to reduce the likelihood of ulcerative cold sores and to shorten the lesion healing time in adults and children (six years of age and older). [61] [62]
Cold sores versus canker sores To make a true diagnosis of the cold sore virus, your doctor needs to take a culture from the area and send it to the lab for analysis, says Dr. Friedman.
Because penciclovir is absorbed poorly when given orally (by mouth) it is more often used as a topical treatment. It is the active ingredient in the cold sore medications Denavir (NDC 0135-0315-52), Vectavir and Fenivir. Famciclovir is a prodrug of penciclovir with improved oral bioavailability. Penciclovir was approved for medical use in 1996. [2]
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