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An axo-axonic synapse is a type of synapse, formed by one neuron projecting its axon terminals onto another neuron's axon. [ 1 ] Axo-axonic synapses have been found and described more recently than the other more familiar types of synapses, such as axo-dendritic synapses and axo-somatic synapses.
A neuromuscular junction (or myoneural junction) is a chemical synapse between a motor neuron and a muscle fiber. [1] It allows the motor neuron to transmit a signal to the muscle fiber, causing muscle contraction. [2] Muscles require innervation to function—and even just to maintain muscle tone, avoiding atrophy.
The sliding filament theory explains the mechanism of muscle contraction based on muscle proteins that slide past each other to generate movement. [1] According to the sliding filament theory, the myosin ( thick filaments ) of muscle fibers slide past the actin ( thin filaments ) during muscle contraction, while the two groups of filaments ...
Signal transmission from nerve to muscle at the motor end plate. The neuromuscular junction is the synapse that is formed between an alpha motor neuron (α-MN) and the skeletal muscle fiber. In order for a muscle to contract, an action potential is first propagated down a nerve until it reaches the axon terminal of the motor neuron.
Depending on whether the damage is to the motor nerves, which regulate movement, or the sensory nerves, which affect the senses, the symptoms of a somatic nervous system problem can differ. [15] Damage to the motor nerves shows as: Loss of movement control; Spasms or cramps in muscles; Tremors or twitching; Wasting of muscles (muscle atrophy)
Depiction of smooth muscle contraction. Muscle contraction is the activation of tension-generating sites within muscle cells. [1] [2] In physiology, muscle contraction does not necessarily mean muscle shortening because muscle tension can be produced without changes in muscle length, such as when holding something heavy in the same position. [1]
The movement of the axons (and subsequently the Schwann cells) is guided by the growth cone, a filamentous projection of the axon that actively searches for neurotrophins released by the myotube. [3] The specific patterning of synapse development at the neuromuscular junction shows that the majority of muscles are innervated at their midpoints.
When a reflex arc in an animal consists of only one sensory neuron and one motor neuron, it is defined as monosynaptic, referring to the presence of a single chemical synapse. In the case of peripheral muscle reflexes (patellar reflex, achilles reflex), brief stimulation to the muscle spindle results in contraction of the agonist or effector ...