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  2. Oncomouse - Wikipedia

    en.wikipedia.org/wiki/Oncomouse

    The OncoMouse or Harvard mouse is a type of laboratory mouse (Mus musculus) that has been genetically modified using modifications designed by Philip Leder and Timothy A Stewart [1] of Harvard University to carry a specific gene called an activated oncogene (v-Ha-ras under the control of the mouse mammary tumor virus promoter).

  3. Genome editing - Wikipedia

    en.wikipedia.org/wiki/Genome_editing

    Genome editing, or genome engineering, or gene editing, is a type of genetic engineering in which DNA is inserted, deleted, modified or replaced in the genome of a living organism. Unlike early genetic engineering techniques that randomly insert genetic material into a host genome, genome editing targets the insertions to site-specific locations.

  4. Gene expression profiling in cancer - Wikipedia

    en.wikipedia.org/wiki/Gene_expression_profiling...

    Of note, similar gene expression patterns associated with metastatic behaviour of breast cancer tumor cells have also been found in breast cancer of dog, the most common tumor of the female dog. [5] [6] Presented below are ways that gene expression profiling has been used to more precisely classify tumors into subgroups, often with clinical effect.

  5. Oncogenomics - Wikipedia

    en.wikipedia.org/wiki/Oncogenomics

    Oncogenomics is a sub-field of genomics that characterizes cancer-associated genes.It focuses on genomic, epigenomic and transcript alterations in cancer. Cancer is a genetic disease caused by accumulation of DNA mutations and epigenetic alterations leading to unrestrained cell proliferation and neoplasm formation.

  6. Human genetic enhancement - Wikipedia

    en.wikipedia.org/wiki/Human_genetic_enhancement

    The burgeoning field of genetic testing and analysis has provided valuable tools for identifying genetic markers associated with various diseases, allowing for proactive measures to be taken in disease prevention [32] Disease prevention via genetic testing is made easier as genetic testing can unveil an individual's genetic susceptibility to ...

  7. List of databases for oncogenomic research - Wikipedia

    en.wikipedia.org/wiki/List_of_databases_for_onco...

    The Cancer Genome Atlas →: National Cancer Institute, United States Copy number, Mutation, Methylation, Gene Expression, miRNA expression: Yes Yes Human: No Yes Yes CancerResource →: University Medicine Berlin, Germany Roche Cancer Genome Database (RCGDB) Roche Diagnostics, Penzberg, Germany Network of Cancer Genes →: King's College ...

  8. Its supporters dream of heat-resistant cows. But gene editing ...

    www.aol.com/news/supporters-dream-heat-resistant...

    A UK law allowing gene-edited food has been paused and some British scientists fear being overtaken. Its supporters dream of heat-resistant cows. But gene editing is making others nervous

  9. Gene therapy - Wikipedia

    en.wikipedia.org/wiki/Gene_therapy

    Cancer gene therapy was introduced in 1992/93 (Trojan et al. 1993). [167] The treatment of glioblastoma multiforme, the malignant brain tumor whose outcome is always fatal, was done using a vector expressing antisense IGF-I RNA (clinical trial approved by NIH protocol no.1602 24 November 1993, [168] and by the FDA in 1994). This therapy also ...