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Mupirocin is used as a topical treatment for bacterial skin infections (for example, boils, impetigo, or open wounds), which are typically due to infection by Staphylococcus aureus or Streptococcus pyogenes. It is also useful in the treatment of superficial methicillin-resistant Staphylococcus aureus (MRSA) infections. [14]
[74] [75] [76] One study found a 44% reduction in bloodstream infection rates when universal decolonization was used (e.g. intranasal mupirocin ointment and chlorhexidine body wash) in a trial involving 73,256 hospital patients. [72]
Fungal skin infections Ciclopirox olamine cream or lotion is used to treat certain dermatophytosis such as tinea pedis, tinea cruris, and tinea corporis. They can also be used for the treatment of cutaneous candidiasis and pityriasis versicolor. The medication is sometimes formulated into gels when treating tinea corporis and interdigital tinea ...
Treatment is typically with antibiotic creams such as mupirocin or fusidic acid. [3] [5] Antibiotics by mouth, such as cefalexin, may be used if large areas are affected. [3] Antibiotic-resistant forms have been found. [3] Healing generally occurs without scarring. [7] Impetigo affected about 140 million people (2% of the world population) in ...
The use of mupirocin ointment can reduce the rate of infections due to nasal carriage of S. aureus. [141] There is limited evidence that nasal decontamination of S. aureus using antibiotics or antiseptics can reduce the rates of surgical site infections. [142]
Mupirocin 2% ointment can be effective at reducing the size of lesions. A secondary covering of clothing is preferred. [ 79 ] As shown in an animal study with diabetic mice, the topical application of a mixture of sugar (70%) and 3% povidone-iodine paste is an effective agent for the treatment of diabetic ulcers with MRSA infection.