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Unstable angina is a type of angina pectoris [1] that is irregular or more easily provoked. [2] It is classified as a type of acute coronary syndrome. [3]
The primary factor differentiating unstable angina from stable angina (other than symptoms) is the underlying pathophysiology of the atherosclerosis. The pathophysiology of unstable angina is the reduction of coronary blood flow due to transient platelet aggregation on apparently normal endothelium, coronary artery spasms, or coronary thrombosis.
In unstable angina, symptoms may appear on rest or on minimal exertion. [6] The symptoms can last longer than those in stable angina, can be resistant to rest or medicine, and can get worse over time. [8] [10] Though ACS is usually associated with coronary thrombosis, it can also be associated with cocaine use. [11]
Rest tends to relieve stable angina, whereas unstable angina and vasospastic angina can occur anytime, including at rest. In terms of medications, all three can be treated with Nitroglycerin which is a vasodilator that increases blood vessel diameter to allow more blood flow. In addition, vasospastic angina also responds to calcium channel ...
Angina may be stable or unstable. Unstable angina is most often associated with emergent, acute coronary syndromes. [20] Angina is typically located below the sternum. [4] Individuals experiencing angina characterize the pain in different ways, but the pain is usually described as crushing, squeezing, or burning. [7]
Angina that changes in intensity, character or frequency is termed unstable. Unstable angina may precede myocardial infarction . In adults who go to the emergency department with an unclear cause of pain, about 30% have pain due to coronary artery disease. [ 29 ]
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