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Fluconazole is an antifungal medication used for a number of fungal infections. [5] This includes candidiasis , blastomycosis , coccidioidomycosis , cryptococcosis , histoplasmosis , dermatophytosis , and tinea versicolor . [ 5 ]
Candidiasis is a fungal infection due to any species of the genus Candida (a yeast). [4] When it affects the mouth, in some countries it is commonly called thrush. [3] Signs and symptoms include white patches on the tongue or other areas of the mouth and throat. [3]
In most cases, the diagnosis is established based on response to therapy. Patients in whom esophageal candidiasis is suspected should receive a brief course of antifungal therapy with fluconazole. If the infection resolves after treatment with fluconazole, then the diagnosis of esophageal candidiasis is made and no further investigation is needed.
Congenital cutaneous candidiasis is a type of candida infection in newborn babies, which appears as generalized red patches and small bumps on the skin or in the mouth, appearing at birth or a few days after birth. [3] [4] It can also occur as more serious widespread disseminated type. [3]
Oral candidiasis (Acute pseudomembranous candidiasis), which is also known as oral thrush, among other names, [1] is candidiasis that occurs in the mouth. That is, oral candidiasis is a mycosis (yeast/fungal infection) of Candida species on the mucous membranes of the mouth .
It is also used in very low birth-weight (less than 1500 g or 3 lb 5oz o) infants to prevent invasive fungal infections, although fluconazole is the preferred treatment. It has been found to reduce the rate of invasive fungal infections and also reduce deaths when used in these babies. [11]
Oral candidiasis (oral thrush), onychomycosis (nail infection), tinea pedis (athlete's foot), Pityriasis Versicolor, tinea capitis, tinea corporis (ringworm), tinea cruris (jock itch) and tinea manuum. Most antifungal agents treat both dermatophyte and yeast infections. However, some, such as nystatin, are not suitable for dermatophyte fungal ...
Many isolates of C. dubliniensis are sensitive to fluconazole.In one study, sixteen of twenty isolates were sensitive to fluconazole, while four were resistant. [5] It has been hypothesized that C. dubliniensis possesses the ability to rapidly develop resistance to fluconazole, especially in patients on long-term therapy.