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An ABPI between and including 0.90 and 1.29 considered normal (free from significant PAD), while a lesser than 0.9 indicates arterial disease. [14] An ABPI value of 1.3 or greater is also considered abnormal, and suggests calcification of the walls of the arteries and incompressible vessels, reflecting severe peripheral vascular disease .
The reversed blood pools in the low third of legs and feet. [17] Unlike in the arterial ultrasound study, when the sonographer studies venous insufficiency, the vein wall itself has no relevance and attention is focused on the direction of blood flow. The objective of the examination is to see how the veins drain.
An eight-week program of brisk walking resulted in a 50% increase in brachial artery FMD in middle-aged and older men, but failed to produce this benefit in estrogen-deficient post-menopausal women. [21] Forty-five minutes of cycling exercise before sitting has been shown to eliminate the impaired leg FMD due to three hours of sitting. [22]
Peripheral arterial disease is more common in these populations: [42] [50] All people who have leg symptoms with exertion (suggestive of claudication) or ischemic rest pain; All people aged 65 years and over, regardless of risk factor status; All people between 50 and 69 who have a cardiovascular risk factor (particularly diabetes or smoking)
Unlike arterial ultrasonography, venous ultrasonography is carried out with the probe in a transversal position, (perpendicular to the vein axis), displaying cross-sections of the veins. [4] All collateral veins are better detected this way, including perforator veins , but of most importance is the detection of venous thrombosis .
The relationship between arterial stiffness and pulse wave velocity was first predicted by Thomas Young in his Croonian Lecture of 1808 [11] but is generally described by the Moens–Korteweg equation [12] or the Bramwell–Hill equation. [13] Typical values of PWV in the aorta range from approximately 5 m/s to >15 m/s. [14]
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Arterial compliance is an index of the elasticity of large arteries such as the thoracic aorta. Arterial compliance is an important cardiovascular risk factor. Compliance diminishes with age and menopause. Arterial compliance is measured by ultrasound as a pressure (carotid artery) and volume (outflow into aorta) relationship. [5]