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Hoofnagle leads the Liver Disease Research Branch at NIDDK, [4] and has done so since he was tapped for the position in 2003. [5] In this capacity, Hoofnagle oversees the Drug-Induced Liver Injury Network and LiverTox, a database that provides "comprehensive and unbiased information about drug induced liver injury caused by prescription and nonprescription drugs, herbal and dietary supplements."
The mission of the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) is to conduct and support medical research and research training and to disseminate science-based information on diabetes and other endocrine and metabolic diseases; digestive diseases, nutritional disorders, and obesity; and kidney, urological, and hematologic diseases, to improve people's health and ...
The National Institutes of Health (NIH) is an agency of the United States Department of Health and Human Services and is the primary agency of the United States government responsible for biomedical and health-related research. [1] It comprises 27 separate institutes and centers (ICs) that carry out its mission in different areas of biomedical ...
CRISP was a fully searchable database of biomedical research projects funded by the U.S. government. It covers projects going back to 1972 and records name and abstract of the project, the principal investigator and the involved institution. The database is maintained by the Office of Extramural Research at the National Institutes of Health.
The databases in the table below are selected from the databases listed in the Nucleic Acids Research (NAR) databases issues and database collection and the databases cross-referenced in the UniProtKB. Most of these databases are cross-referenced with UniProt / UniProtKB so that identifiers can be mapped to each other. [15] Proteins in human:
LiverTox: Clinical and Research Information on Drug-Induced Liver Injury. Bethesda, MD: National Institute of Diabetes and Digestive and Kidney Diseases. October 2019. PMID 31869194. NBK551730. Lamb YN (November 2019). "Pexidartinib: First Approval". Drugs. 79 (16): 1805– 1812. doi: 10.1007/s40265-019-01210-0. PMC 7044138. PMID 31602563.
National Center for Biotechnology Information is an intramural division within National Library of Medicine that creates public databases in molecular biology, conducts research in computational biology, develops software tools for analyzing molecular and genomic data, and disseminates biomedical information, all for the better understanding of ...
Hepatotoxicity (from hepatic toxicity) implies chemical-driven liver damage. Drug-induced liver injury (DILI) is a cause of acute and chronic liver disease caused specifically by medications and the most common reason for a drug to be withdrawn from the market after approval.