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The symptoms of PCCI were recognized by researchers in the 1980s, who typically described it as mild cognitive impairment subsequent to successful cancer treatment. [4] Some authors say that it was identified primarily in breast cancer survivor and support groups as affecting a subset of individuals treated with chemotherapy , who attributed it ...
Alpha 1 blockers cause vasodilation by relaxing smooth muscles that control blood vessel diameter, leading to lower blood pressure. [1] FDA-approved uses of these drugs include treating conditions like benign prostatic hyperplasia, hypertension, pheochromocytoma, extravasation management, and reversal of local anesthesia.
With treatment, about 80% of cases have a good outcome. [1] Outcomes are better if treatment is begun earlier. [2] Long-term mental or behavioral problems may remain. [2] About 4% of those affected die from the condition. [2] Recurrence occurs in about 10% of people. [1] The estimated number of cases of the disease is one in 1.5 million people ...
Dr. Ahluwalia says that the earliest symptoms of brain cancer depend on the size and location of the brain tumor. “Often, one of the first symptoms is a seizure, which is caused by abnormal ...
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The DNA repair function of alpha-synuclein appears to be compromised in Lewy body inclusion bearing neurons, and this may trigger cell death. Study of synucleinopathy mouse models of Parkinson's disease indicates that alpha-synuclein pathogenesis is associated with increased DNA damage and activation of the DNA damage response. [19]