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  2. B7 (protein) - Wikipedia

    en.wikipedia.org/wiki/B7_(protein)

    B7 is a type of integral membrane protein found on activated antigen-presenting cells (APC) that, when paired with either a CD28 or CD152 (CTLA-4) surface protein on a T cell, can produce a costimulatory signal or a coinhibitory signal to enhance or decrease the activity of a MHC - TCR signal between the APC and the T cell, respectively.

  3. Molecules (journal) - Wikipedia

    en.wikipedia.org/wiki/Molecules_(journal)

    Molecules is a peer-reviewed open access scientific journal that focuses on all aspects of chemistry and materials science. It was established in March 1996 and is published monthly by MDPI . From 1997 to 2001, Molbank was published as a section of the journal, before splitting into its own journal.

  4. MDPI - Wikipedia

    en.wikipedia.org/wiki/MDPI

    MDPI. MDPI (Multidisciplinary Digital Publishing Institute) is a publisher of open-access scientific journals. It publishes over 390 peer-reviewed, open access journals. [2][3] MDPI is among the largest publishers in the world in terms of journal article output, [4][5] and is the largest publisher of open access articles.

  5. Anaphase-promoting complex - Wikipedia

    en.wikipedia.org/wiki/Anaphase-promoting_complex

    Anaphase-promoting complex (also called the cyclosome or APC/C) is an E3 ubiquitin ligase that marks target cell cycle proteins for degradation by the 26S proteasome. The APC/C is a large complex of 11–13 subunit proteins, including a cullin (Apc2) and RING (Apc11) subunit much like SCF. Other parts of the APC/C have unknown functions but are ...

  6. International Journal of Molecular Sciences - Wikipedia

    en.wikipedia.org/wiki/International_Journal_of...

    The International Journal of Molecular Sciences is a peer-reviewed open access scientific journal covering research in chemistry, molecular physics, and molecular biology. It is published by MDPI and was established in 2000. The journal is considered one of MDPI's flagship publications. [1]

  7. Artificial antigen presenting cells - Wikipedia

    en.wikipedia.org/wiki/Artificial_antigen...

    T cells need another signal to become activated in addition to Signal 1, this is done by co-stimulatory molecules such as the proteins CD80 (B7.1) or CD86 (B7.2), although other additional co-stimulation molecules have been identified. When Signal 2 is not expressed, but T cells receive Signal 1, the antigen-specific T cells become anergic and ...

  8. Protein C - Wikipedia

    en.wikipedia.org/wiki/Protein_C

    Protein C. Protein C, also known as autoprothrombin IIA and blood coagulation factor XIV, [5]: 6822 [6] is a zymogen, that is, an inactive enzyme. The activated form plays an important role in regulating anticoagulation, inflammation, and cell death and maintaining the permeability of blood vessel walls in humans and other animals.

  9. Antigen-presenting cell - Wikipedia

    en.wikipedia.org/wiki/Antigen-presenting_cell

    An antigen-presenting cell (APC) or accessory cell is a cell that displays an antigen bound by major histocompatibility complex (MHC) proteins on its surface; this process is known as antigen presentation. T cells may recognize these complexes using their T cell receptors (TCRs). APCs process antigens and present them to T cells.