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In dermatology, a mole map is a medical record which records an image and the location of lesions and/or moles, or dark spots on the human body. Such a record is useful for diagnosis of cancer a priori or as a baseline which can be compared against later images to determine when there has been a visual change which may indicate cancer.
A mole can be either subdermal (under the skin) or a pigmented growth on the skin, formed mostly of a type of cell known as a melanocyte. The high concentration of the body's pigmenting agent, melanin, is responsible for their dark color. Moles are a member of the family of skin lesions known as nevi (singular "nevus"), occurring commonly in ...
Various differential diagnoses of pigmented skin lesions, by relative rates upon biopsy and malignancy potential, including "melanoma" at right. Looking at or visually inspecting the area in question is the most common method of suspecting a melanoma. [68] Moles that are irregular in color or shape are typically treated as candidates.
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Nevus (pl.: nevi) is a nonspecific medical term for a visible, circumscribed, chronic lesion of the skin or mucosa. [1] The term originates from nævus, which is Latin for "birthmark"; however, a nevus can be either congenital (present at birth) or acquired.
Richard A.F. Clark is a dermatologist and biomedical engineer currently at the State University of New York at Stony Brook [1] in Stony Brook, New York. [2] Clark co-edited, with Peter M. Henson, of The Molecular and Cellular Biology of Wound Repair (Plenum Press, 1988) and is a contributor to wound repair, dermatology, and angiogenesis research.
The CDKN2A gene is located on chromosome 9p21.3. Two main transcripts, isoforms '1' and '4', each contain three exons and span 7288 and 26740 bp, respectively. They encode proteins of 156 and 173 amino acids; isoform '1' encodes p16(INK4a), while isoform '4' encodes p14(ARF), a protein that is structurally unrelated to p16(INK4) but acts in cell cycle G1 control by stabilizing the tumor ...
Skin grafts and local skin flaps are by far more common than the other listed choices. Skin grafting is patching of a defect with skin that is removed from another site in the body. The skin graft is sutured to the edges of the defect, and a bolster dressing is placed atop the graft for seven to ten days, to immobilize the graft as it heals in ...