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The incidence of age-related macular degeneration and its associated features increases with age and is low in people <55 years of age. [101] Smoking is the strongest modifiable risk factor. [ 102 ] As of 2008, age-related macular degeneration accounts for more than 54% of all vision loss in the white population in the US. [ 103 ]
AMD Alliance International is a non-profit coalition of the world’s leading vision, seniors and research organizations working to raise awareness of age-related macular degeneration, understanding of available options for prevention, early detection, treatment, rehabilitation and support services.
In persons who are over 65 years old, age-related macular degeneration is the leading cause of severe vision loss. A subtype of age-related macular degeneration, wet macular degeneration, is characterized by the formation of new blood vessels that originate in the choroidal vasculature and extend into the subretinal space. [5]
Carotenoids lutein and zeaxanthin, found in the yolk of chicken eggs, have been shown to reduce the risk of cataracts and macular degeneration, the leading causes of blindness in people 55 and older.
Age-related macular degeneration, glaucoma, and diabetic retinopathy are the leading causes of blindness in the developed world. [54] Among working-age adults who are newly blind in England and Wales the most common causes in 2010 were: [55] Hereditary retinal disorders (20.2%) Diabetic retinopathy (14.4%) Optic atrophy (14.1%) Glaucoma (5.9%)
Geographic atrophy (GA), also known as atrophic age-related macular degeneration (AMD) or advanced dry AMD, is an advanced form of age-related macular degeneration that can result in the progressive and irreversible loss of retinal tissue (photoreceptors, retinal pigment epithelium, choriocapillaris) which can lead to a loss of central vision over time.
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