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Donating plasma is similar in many ways to whole blood donation, though the end product is used for different purposes. Most plasmapheresis is for fractionation into other products; other blood donations are transfused with relatively minor modifications. Plasma that is collected solely for further manufacturing is called Source Plasma.
When donating whole blood or packed red blood cell (PRBC) transfusions, O-is the most desirable and is considered a "universal donor," since it has neither A nor B antigens and can be safely transfused to most recipients. Type AB+ is the "universal recipient" type for PRBC donations. However, for plasma the situation is somewhat reversed.
[2] [4] Using ABO compatible plasma, while not required, may be recommended. [5] [6] Use as a volume expander is not recommended. [3] It is administered by slow injection into a vein. [2] Side effects include nausea and itchiness. [3] Rarely there may be allergic reactions, blood clots, or infections.
Some donors have reported feeling queasy or lightheaded after the process, but plasma donation centers are very efficient and have medical staff on hand to deal with any side effects patients ...
With plasma frequently in short supply, collection centers are more than willing to pay you for your time in making the donation, which in turn can make this a kind of "side hustle" for you.
The difference with plasma donation is that the blood goes through a machine that collects only the plasma and sends the red and white blood cells and platelets back to the donor in a saline solution.
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