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A urinary tract infection (UTI) is an infection that affects a part of the urinary tract. [1] Lower urinary tract infections may involve the bladder (cystitis) or urethra while upper urinary tract infections affect the kidney (pyelonephritis). [10]
Urinary tract infection in pediatric patients is a significant clinical issue, affecting approximately 7% of fevered infants and children. [43] If left untreated, the infection can ascend from the bladder to the kidneys, resulting in acute pyelonephritis, which leads to hypertension , kidney scarring , and end-stage kidney disease .
For men, the signs and symptoms are discharge from the penis, burning or pain when urinating, itching, irritation, or tenderness. In women, the signs and symptoms are discharge from vagina, burning or pain when urinating, anal or oral infections, abdominal pain, or abnormal vaginal bleeding, which may be an indication that the infection has ...
The estimated global prevalence of gonorrhoea is 0.9% in women and 0.7% in men. An estimated 87 million new infections of gonorrhoea occurred in 2016. Low-income countries have the highest prevalence of gonorrhoea. [24] Gonorrhea is more commonly seen in males than in females and infection rates are higher in adolescents and young adults. [1]
Researchers in the United States and United Kingdom have shown how the bacteria responsible for many urinary tract infections have adapted to prevent being flushed out when you pee.
Uromune, also known by its developmental code name MV-140, is a polyvalent bacterial vaccine which is used and is being developed for prevention of recurrent urinary tract infections (UTIs). [ 1 ] [ 2 ] [ 3 ] In clinical studies , it has been found to reduce total number of UTIs by about 70%, to increase UTI-free rates from around 25% to 57% ...