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Along with heavy metal poisoning, Roach says chelation therapy is also sometimes used when you have “iron overload”—when the body has too much iron and can’t get rid of it naturally ...
Chelation therapy is a medical procedure that involves the administration of chelating agents to remove heavy metals from the body. [1] Chelation therapy has a long history of use in clinical toxicology [2] and remains in use for some very specific medical treatments, although it is administered under very careful medical supervision due to various inherent risks, including the mobilization of ...
Typical treatment for chronic iron overload requires subcutaneous injection over a period of 8–12 hours daily. [citation needed] Two newer iron-chelating drugs that are licensed for use in patients receiving regular blood transfusions to treat thalassaemia (and, thus, who develop iron overload as a result) are deferasirox and deferiprone. [47 ...
Deferiprone, sold under the brand name Ferriprox among others, is a medication that chelates iron and is used to treat iron overload in thalassaemia major. [5] It was first approved and indicated for use in treating thalassaemia major in 1994 [6] and had been licensed for use in the European Union for many years while awaiting approval in Canada and in the United States. [5]
Chelation therapy removes iron from the blood. [5] This involves delivering iron chelating agents such as deferoxamine, deferiprone or deferasirox. [5] If iron overload has caused damage to end-organs, this is generally irreversible and may require transplantation. [clarification needed]
For more severe forms, treatment may consist in blood transfusion; chelation therapy to reverse iron overload, using drugs such as deferoxamine, deferiprone, or deferasirox; medication with the antioxidant indicaxanthin to prevent the breakdown of hemoglobin; or a bone marrow transplant using material from a compatible donor, or from the ...
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