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  2. Gene therapy for blood diseases - Wikipedia

    en.wikipedia.org/wiki/Gene_therapy_for_blood...

    The genetically modified T-cells are administered back to the patients as a treatment. Leukemia is a group of blood cancers commonly found in children younger than 15 and elders older than 55. [ 3 ] In 2017, tisagenlecleucel (Kymriah™) , [ 2 ] the first CAR-T cell therapy approved by the FDA , became available to anyone up to the age of 25 ...

  3. Gene editing saves a human life for the first time - AOL

    www.aol.com/news/2015-11-06-gene-editing-saves-a...

    With the permission of Layla's parents, doctors tested an experimental form of gene therapy on the 1-year-old by using genetically engineered immune cells from a donor. Within one month, all of ...

  4. Leukemia - Wikipedia

    en.wikipedia.org/wiki/Leukemia

    In addition to these genetic issues, people with chromosomal abnormalities or certain other genetic conditions have a greater risk of leukemia. [47] For example, people with Down syndrome have a significantly increased risk of developing forms of acute leukemia (especially acute myeloid leukemia ), and Fanconi anemia is a risk factor for ...

  5. Gene therapy - Wikipedia

    en.wikipedia.org/wiki/Gene_therapy

    In March researchers reported that three of five adult subjects who had acute lymphocytic leukemia (ALL) had been in remission for five months to two years after being treated with genetically modified T cells which attacked cells with CD19 genes on their surface, i.e. all B cells, cancerous or not. The researchers believed that the patients ...

  6. Genome editing - Wikipedia

    en.wikipedia.org/wiki/Genome_editing

    Genome editing, or genome engineering, or gene editing, is a type of genetic engineering in which DNA is inserted, deleted, modified or replaced in the genome of a living organism. Unlike early genetic engineering techniques that randomly insert genetic material into a host genome, genome editing targets the insertions to site-specific locations.

  7. Chronic lymphocytic leukemia - Wikipedia

    en.wikipedia.org/wiki/Chronic_lymphocytic_leukemia

    [34] [35] Some relevant genetic mutations may be inherited. Since there is no one single mutation that is associated with CLL in all cases, an individual's susceptibility may be impacted when multiple mutations that are associated with an increase in the risk of CLL are co-inherited. [36] Up until 2020, 45 susceptibility loci have been identified.

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