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The project makes all sequence data publicly available through GenBank, an international, NIH-funded, searchable online database.This research helps to provide international researchers with the information needed to develop new vaccines, therapies and diagnostics, as well as improve understanding of the overall molecular evolution of Influenza and other genetic factors that determine their ...
Viral phylodynamics is the study of how epidemiological, immunological, and evolutionary processes act and potentially interact to shape viral phylogenies. [1] Since the term was coined in 2004, research on viral phylodynamics has focused on transmission dynamics in an effort to shed light on how these dynamics impact viral genetic variation.
Influenza B virus is almost exclusively a human pathogen, and is less common than influenza A. The only other animal known to be susceptible to influenza B infection is the seal. [47] This type of influenza mutates at a rate 2–3 times lower than type A [48] and consequently is less genetically diverse, with only one influenza B serotype. [26]
Influenza viruses A and B are estimated to have diverged from a single ancestor around 4,000 years ago, while the ancestor of influenza viruses A and B and the ancestor of influenza virus C are estimated to have diverged from a common ancestor around 8,000 years ago. [41] Outbreaks of influenza-like disease can be found throughout recorded history.
Influenza A virus subtype H5N1 (A/H5N1) is a subtype of the influenza A virus, which causes influenza (flu), predominantly in birds. It is enzootic (maintained in the population) in many bird populations, and also panzootic (affecting animals of many species over a wide area). [1]
GISAID (/ ˈ ɡ ɪ s eɪ d /), the Global Initiative on Sharing All Influenza Data, [9] previously the Global Initiative on Sharing Avian Influenza Data, [10] [11] is a global science initiative established in 2008 to provide access to genomic data of influenza viruses.
On Thursday, Roche Holdings AG (OTC:RHHBY) released positive topline results of the phase 3 CENTERSTONE study of Xofluza (baloxavir marboxil), an antiviral that showed a reduction in the ...
[23] [26] Influenza D virus is distantly related to influenza C virus. While cattle workers have occasionally tested positive to prior influenza D virus infection, it is not known to cause disease in humans. [1] [11] [12] Influenza C virus and influenza D virus experience a slower rate of antigenic evolution than influenza A virus and influenza ...