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The Nun Study of Aging and Alzheimer's Disease is a continuing longitudinal study, begun in 1986, to examine the onset of Alzheimer's disease. [1] [2] David Snowdon, an Epidemiologist and the founding Nun Study investigator, started the Nun Study at the University of Minnesota, later transferring the study to the University of Kentucky in 1990. [3]
A longitudinal study (or longitudinal survey, or panel study) is a research design that involves repeated observations of the same variables (e.g., people) over long periods of time (i.e., uses longitudinal data). It is often a type of observational study, although it can also be structured as longitudinal randomized experiment. [1]
Longitudinal research studies have recently conducted genetic analyses of centenarians and their offspring to identify protective factors against the negative effects of aging. In particular, the CETP gene is linked to prevention of cognitive decline and Alzheimer's disease. [ 90 ]
By their usual definitions, childhood dementias always cause global neurocognitive decline. In some childhood dementia conditions the child's early development is indistinguishable from their healthy peers, then slows or plateaus before declining. In other childhood dementia disorders, early development may be slower than typical before declining.
Regarding incidence, cohort longitudinal studies (studies where a disease-free population is followed over the years) provide rates between 10 and 15 per thousand person-years for all dementias and 5–8 for AD, [235] [236] which means that half of new dementia cases each year are Alzheimer's disease. Advancing age is a primary risk factor for ...
Another study published in Sleep Medicine Reviews found that sleep disturbances may predict an increased risk of dementia. The new study showed a connection between daytime sleepiness and motoric ...
The development of memory is a lifelong process that continues through adulthood. Development etymologically refers to a progressive unfolding. Memory development tends to focus on periods of infancy, toddlers, children, and adolescents, yet the developmental progression of memory in adults and older adults is also circumscribed under the umbrella of memory development.
Reminiscence therapy is credited to the work of Dr. Robert Butler, a psychiatrist in the field of geriatric medicine in the 1960s, and is sometimes called life review therapy.It can be a helpful ...