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  2. NCI-60 - Wikipedia

    en.wikipedia.org/wiki/NCI-60

    Originally the cell line was named MCF-7/ADR-RES; it was renamed together with the change in classification. [8] Two brain cancer cell lines, SNB-19 and U251, were discovered to come from the same person. [9] This makes a mixup likely. A 61st cell line, MDA-N, has been confirmed to being derived from the misclassified MDA-MB-435 cell line. [7]

  3. Pleomorphism (cytology) - Wikipedia

    en.wikipedia.org/wiki/Pleomorphism_(cytology)

    Pleomorphism is a term used in histology and cytopathology to describe variability in the size, shape and staining of cells and/or their nuclei. Several key determinants of cell and nuclear size, like ploidy and the regulation of cellular metabolism , are commonly disrupted in tumors . [ 1 ]

  4. Bi-specific T-cell engager - Wikipedia

    en.wikipedia.org/wiki/Bi-specific_T-cell_engager

    Bi-specific T-cell engager (BiTE) is a class of artificial bispecific monoclonal antibodies that are investigated for use as anti-cancer drugs. They direct a host's immune system, more specifically the T cells ' cytotoxic activity, against cancer cells.

  5. List of breast cancer cell lines - Wikipedia

    en.wikipedia.org/wiki/List_of_breast_cancer_cell...

    Scientists study the behaviour of isolated cells grown in the laboratory for insights into how cells function in the body in health and disease. Experiments using cell culture are used for developing new diagnostic tests and new treatments for diseases. This is a list of major breast cancer cell lines that are primarily used in breast cancer ...

  6. Auger therapy - Wikipedia

    en.wikipedia.org/wiki/Auger_Therapy

    Due to their low kinetic energy, emitted Auger electrons travel over a very short range: much less than the size of a single cell, on the order of less than a few-hundred nanometers. [4] This very short-range delivery of energy permits highly targeted therapies, since the radiation-emitting nuclide will be in close proximity to the delivery ...

  7. A549 cell - Wikipedia

    en.wikipedia.org/wiki/A549_cell

    A549 cells are adenocarcinomic human alveolar basal epithelial cells, and constitute a cell line that was first developed in 1972 by D. J. Giard, et al. through the removal and culturing of cancerous lung tissue in the explanted tumor of a 58-year-old caucasian male. [1]

  8. Cytokine-induced killer cell - Wikipedia

    en.wikipedia.org/wiki/Cytokine-induced_killer_cell

    Cytokine-induced killer cells (CIK) cells are a group of immune effector cells featuring a mixed T- and natural killer (NK) cell-like phenotype.They are generated by ex vivo incubation of human peripheral blood mononuclear cells (PBMC) or cord blood mononuclear cells with interferon-gamma (), anti-CD3 antibody, recombinant human interleukin (IL)-1 and recombinant human interleukin (IL)-2.

  9. Extracellular vesicle - Wikipedia

    en.wikipedia.org/wiki/Extracellular_vesicle

    Extracellular vesicles (EVs) are lipid bilayer-delimited particles that are naturally released from almost all types of cells but, unlike a cell, cannot replicate. EVs range in diameter from near the size of the smallest physically possible unilamellar liposome (around 20-30 nanometers) to as large as 10 microns or more, although the vast majority of EVs are smaller than 200 nm.