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  2. Phenoxyethanol - Wikipedia

    en.wikipedia.org/wiki/Phenoxyethanol

    Phenoxyethanol has germicidal and germistatic properties. [6] It is often used together with quaternary ammonium compounds.. Phenoxyethanol is used as a perfume fixative; an insect repellent; an antiseptic; [7] a solvent for cellulose acetate, dyes, inks, and resins; a preservative for pharmaceuticals, cosmetics and lubricants; [8] an anesthetic in fish aquaculture; [9] [10] and in organic ...

  3. p-Phenylenediamine - Wikipedia

    en.wikipedia.org/wiki/P-Phenylenediamine

    p-Phenylenediamine (PPD) is an organic compound with the formula C 6 H 4 (NH 2) 2. This derivative of aniline is a white solid, but samples can darken due to air oxidation. [ 1 ] It is mainly used as a component of engineering polymers and composites like kevlar .

  4. Preclinical development - Wikipedia

    en.wikipedia.org/wiki/Preclinical_development

    In drug development, preclinical development (also termed preclinical studies or nonclinical studies) is a stage of research that begins before clinical trials (testing in humans) and during which important feasibility, iterative testing and drug safety data are collected, typically in laboratory animals.

  5. Drug development - Wikipedia

    en.wikipedia.org/wiki/Drug_development

    Drug development is the process of bringing a new pharmaceutical drug to the market once a lead compound has been identified through the process of drug discovery.It includes preclinical research on microorganisms and animals, filing for regulatory status, such as via the United States Food and Drug Administration for an investigational new drug to initiate clinical trials on humans, and may ...

  6. Toxicology testing - Wikipedia

    en.wikipedia.org/wiki/Toxicology_testing

    Toxicology testing is commonly conducted during preclinical development for a substance intended for human exposure. Stages of in silico, in vitro and in vivo research are conducted to determine safe exposure doses in model organisms. If necessary, the next phase of research involves human toxicology testing during a first-in-man study.

  7. Experimental drug - Wikipedia

    en.wikipedia.org/wiki/Experimental_drug

    In the United States, the body responsible for approval is the Food and Drug Administration (FDA), which must grant the substance Investigational New Drug (IND) status before it can be tested in human clinical trials. IND status requires the drug's sponsor to submit an IND application that includes data from laboratory and animal testing for ...

  8. Dying To Be Free - The Huffington Post

    projects.huffingtonpost.com/dying-to-be-free...

    The addiction involves genetic predisposition, corrupted brain chemistry, entrenched environmental factors and any number of potential mental-health disorders — it requires urgent medical intervention. According to the medical establishment, medication coupled with counseling is the most effective form of treatment for opioid addiction.

  9. Glossary of clinical research - Wikipedia

    en.wikipedia.org/wiki/Glossary_of_clinical_research

    Refers to the practices and procedures used for the prevention, treatment, or relief of symptoms of a diseases or abnormal conditions. This term may also refer to a legal drug used for the same purpose. (NCI) Meta-analysis The formal evaluation of the quantitative evidence from two or more trials bearing on the same question.

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