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Alpha-thalassemia (α-thalassemia, α-thalassaemia) is an inherited blood disorder and a form of thalassemia.Thalassemias are a group of inherited blood conditions which result in the impaired production of hemoglobin, the molecule that carries oxygen in the blood. [4]
Eric S. Hatch (October 31, 1901 - July 4, 1973) was an American writer on the staff of The New Yorker and a novelist and screenwriter best known for his novels 1101 Park Avenue, (which became the hit 1936 film, My Man Godfrey) and The Year of the Horse (adapted as the 1968 Disney comedy, The Horse in the Gray Flannel Suit).
The R-Smads consist of Smad1, Smad2, Smad3, Smad5 and Smad8/9, [3] and are involved in direct signaling from the TGF-B receptor. [4]Smad4 is the only known human Co-Smad, and has the role of partnering with R-Smads to recruit co-regulators to the complex.
20512 Ensembl ENSG00000079215 ENSMUSG00000005360 UniProt P43003 P56564 RefSeq (mRNA) NM_001166695 NM_001166696 NM_001289939 NM_001289940 NM_004172 NM_148938 RefSeq (protein) NP_001160167 NP_001160168 NP_001276868 NP_001276869 NP_004163 NP_683740 Location (UCSC) Chr 5: 36.6 – 36.69 Mb Chr 15: 8.66 – 8.74 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Excitatory amino acid ...
Chromatin remodeling is the dynamic modification of chromatin architecture to allow access of condensed genomic DNA to the regulatory transcription machinery proteins, and thereby control gene expression.
Incomplete lineage sorting (ILS) [1] [2] [3] (also referred to as hemiplasy, deep coalescence, retention of ancestral polymorphism, or trans-species polymorphism) is a phenomenon in evolutionary biology and population genetics that results in discordance between species and gene trees.
11604 Ensembl ENSG00000159723 ENSMUSG00000005705 UniProt O00253 P56473 RefSeq (mRNA) NM_001138 NM_001271806 NM_007427 RefSeq (protein) NP_001129 NP_001258735 NP_031453 Location (UCSC) Chr 16: 67.48 – 67.48 Mb Chr 8: 106.29 – 106.36 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Agouti-related protein (AgRP), also called agouti-related peptide, is a neuropeptide produced in the ...
Pseudogenes are nonfunctional segments of DNA that resemble functional genes.Pseudogenes can be formed from both protein-coding genes and non-coding genes. In the case of protein-coding genes, most pseudogenes arise as superfluous copies of functional genes, either directly by gene duplication or indirectly by reverse transcription of an mRNA transcript.