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Mucociliary clearance has a major role in pulmonary hygiene. MCC effectiveness relies on the correct properties of the airway surface liquid produced, both of the periciliary sol layer and the overlying mucus gel layer, and of the number and quality of the cilia present in the lining of the airways. [3] An important factor is the rate of mucin ...
The Medicines Control Agency (MCA) and the Medical Devices Agency (MDA) merged in 2003 to form MHRA. In April 2012, the GPRD was rebranded as the Clinical Practice Research Datalink (CPRD). In April 2013, MHRA merged with the National Institute for Biological Standards and Control (NIBSC) and was rebranded, with the MHRA identity being used for ...
Airway clearance therapy is treatment that uses a number of airway clearance techniques to clear the respiratory airways of mucus and other secretions. [1] Several respiratory diseases cause the normal mucociliary clearance mechanism to become impaired resulting in a build-up of mucus which obstructs breathing, and also affects the cough reflex .
The development of heated humidified high flow started in 1999 with Vapotherm introducing the concept of high flow use with race horses. [2]High flow was approved by the U.S. Food and Drug Administration in the early 2000s and used as an alternative to positive airway pressure for treatment of apnea of prematurity in neonates. [3]
The trust was formed on 1 July 2006, following the merger of the Hereford & Worcester Ambulance Service NHS Trust, Coventry & Warwickshire Ambulance NHS Trust, and WMAS and Shropshire services. [3] On 1 October 2007, the service merged with Staffordshire Ambulance Service NHS Trust. [3] [4] It became an NHS foundation trust on 1 January 2013. [5]
Mucoadhesion involves several types of bonding mechanisms, and it is the interaction between each process that allows for the adhesive process. The major categories are wetting theory, adsorption theory, diffusion theory, electrostatic theory, and fracture theory. [5]
University College London Hospitals NHS Foundation Trust (UCLH) is an NHS foundation trust based in London, United Kingdom.It comprises University College Hospital, University College Hospital at Westmoreland Street, the UCH Macmillan Cancer Centre, the Royal National ENT and Eastman Dental Hospitals, the Hospital for Tropical Diseases, the National Hospital for Neurology and Neurosurgery, the ...
North West Boroughs Healthcare NHS Foundation Trust was an NHS foundation trust which provided mental health, learning disability and community health services in fifteen boroughs of North West England. The Trust delivered mental health and learning disability services in Halton, Knowsley, St Helens, Warrington and Wigan, as well as community ...