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Illustration of a melanocyte Micrograph of melanocytes in the epidermis. Through a process called melanogenesis, melanocytes produce melanin, which is a pigment found in the skin, eyes, hair, nasal cavity, and inner ear. This melanogenesis leads to a long-lasting pigmentation, which is in contrast to the pigmentation that originates from ...
This is an accepted version of this page This is the latest accepted revision, reviewed on 11 February 2025. "Skin pigmentation" redirects here. For animal skin pigmentation, see Biological pigment. Extended Coloured family from South Africa showing some spectrum of human skin coloration Human skin color ranges from the darkest brown to the lightest hues. Differences in skin color among ...
Albinism occurs when melanocytes produce little melanin. This albino girl is from Papua New Guinea. In humans, melanin is the primary determinant of skin color. It is also found in hair, the pigmented tissue underlying the iris of the eye, and the stria vascularis of the inner ear.
Along the junction of the epidermis and the underlying dermis. [15] May be colored and slightly raised. [16] ICD10: D22 ICDO: M8740/0 Compound nevus Both the epidermis and dermis. [17] ICD10: D22 (ILDS D22.L14) ICDO: 8760/0 Intradermal nevus Within the dermis. A classic mole or birthmark. It typically appears as an elevated, dome-shaped bump on ...
The dermis contains two vascular networks that run parallel to the skin surface—one superficial and one deep plexus—which are connected by vertical communicating vessels. [8] [11] The function of blood vessels within the dermis is fourfold: to supply nutrition, to regulate temperature, to modulate inflammation, and to participate in wound ...
The dermis is composed of three major types of cells: [3] fibroblasts, macrophages, and mast cells.. Apart from these cells, the dermis is also composed of matrix components such as collagen (which provides strength), elastin (which provides elasticity), and extrafibrillar matrix, an extracellular gel-like substance primarily composed of glycosaminoglycans (most notably hyaluronan ...
Mongolian spot is a congenital developmental condition—that is, one existing from birth—exclusively involving the skin.The blue colour is caused by melanocytes, melanin-containing cells, that are usually located in the surface of the skin (the epidermis), but are in the deeper region (the dermis) in the location of the spot. [6]
One study compared the two shapes and recorded data that showed spherical particles located deep in the epidermis and dermis whereas ellipsoidal particles were mainly found in the stratum corneum and epidermal layers. [48] Nanorods are used in experiments because of their unique fluorescent properties but have shown mediocre penetration.