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The Guinea pig maximisation test (GPMT) is an in vivo test to screen for substances that cause human skin sensitisation (i.e. allergens). It was first proposed by B. Magnusson and Albert Kligman in 1969 [ 1 ] and described in their 1970 book Allergic Contact Dermatitis in the Guinea Pig .
The Buehler test is an in vivo test to screen for substances that cause human skin sensitisation (i.e. allergens). It was first proposed by Edwin Vernon Buehler in 1965 [1] and further explained in 1980. [2] It is a non-adjuvant test. In the test, guinea pigs are exposed to a high dose of the substance.
Currently, rodents are commonly used in animal testing for physiological, pathological and behavioral scientific studies, particularly mice and rats, but also guinea pigs, hamsters, gerbils and others. Mice are the most commonly used vertebrate species, due to their availability, size, low cost, ease of handling, and fast reproduction rate
In English, the term "guinea pig" is commonly used as a metaphor for a subject of scientific experimentation, or in modern times a subject of any experiment or test. This usage dates back to the early 20th century: the earliest examples cited by the Oxford English Dictionary date from 1913 and 1920. [ 182 ]
The terms animal testing, animal experimentation, animal research, in vivo testing, and vivisection have similar denotations but different connotations.Literally, "vivisection" means "live sectioning" of an animal, and historically referred only to experiments that involved the dissection of live animals.
A guinea pig is a domestic rodent. Guinea pig may also refer to: Guinea pig, a colloquial term for a test subject of any species: Human subject research; Animal testing; The Guinea Pig Club, a group of surgical patients; 100,000,000 Guinea Pigs, a 1933 book about the pharmaceutical and food industries; Guinea Pig (film series), a controversial ...
A Sheltie guinea pig with lilac and white coloring. Guinea Pigs, also known as cavies (Cavia porcellus), have been domesticated since around (or cicra) 5000 BCE, leading to the development of a diverse array of breeds. These breeds exhibit a wide range of physical characteristics and serve various purposes.
Cavia is a genus in the subfamily Caviinae that contains the rodents commonly known as the true guinea pigs or cavies. [1] The best-known species in this genus is the domestic guinea pig, Cavia porcellus, a meat animal in South America and a common household pet outside that continent.