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Zinc fingers help read DNA sequences.. Zinc is an essential trace element for humans [1] [2] [3] and other animals, [4] for plants [5] and for microorganisms. [6] Zinc is required for the function of over 300 enzymes and 1000 transcription factors, [3] and is stored and transferred in metallothioneins.
Zinc deficiency is defined either as insufficient zinc to meet the needs of the body, or as a serum zinc level below the normal range. However, since a decrease in the serum concentration is only detectable after long-term or severe depletion, serum zinc is not a reliable biomarker for zinc status. [1]
Following an oral intake of extremely high doses of zinc (where 300 mg Zn/d – 20 times the US RDA – is a "low intake" overdose [1]), nausea, vomiting, pain, cramps, and diarrhea may occur. [1] There is evidence of induced copper deficiency , alterations of blood lipoprotein levels, increased levels of LDL , and decreased levels of HDL at ...
Porphyrin complexes of zinc have been known since the 1930s. [1] In 1974 ZPP was identified as a major non-heme porphyrin formed in red cells as the result of lead poisoning or iron deficiency., [8] It was already known at this time that non-heme protoporphyrin IX levels were elevated in these conditions, but prior investigators had used acidic extraction methods in their assays that converted ...
Nutritional anemia can be caused by a lack of iron, protein, vitamin B12, and other vitamins and minerals that are needed for the formation of hemoglobin. However, Iron deficiency anemia is the most common nutritional disorder. [7] Signs of anemia include cyanosis, jaundice, and easy bruising. [7]
usually the anion Zn(OH) 4 2−, more properly called tetrahydroxozincate or salts thereof, such as sodium zincate Na 2 Zn(OH) 4. the polymeric anion [Zn(OH) 3 −] and its salts, for example NaZn(OH) 3 · H 2 O. [1] an oxide containing zinc and a less electronegative element e.g. Na 2 ZnO 2. [2]
Zn, the most abundant isotope of zinc, is very susceptible to neutron activation, being transmuted into the highly radioactive 65 Zn, which has a half-life of 244 days and produces intense gamma radiation. Because of this, zinc oxide used in nuclear reactors as an anti-corrosion agent is depleted of 64 Zn before use, this is called depleted ...
For example, terpyridine, which is a tridentate ligand forms the complex [Zn(terpy)Cl 2]. Another example would involve a tripodal ligand such as Tris(2-aminoethyl)amine. Square pyramidal 5-coordinate Zinc is found in Tetra(4-pyridyl)porphinatomonopyridinezinc(II) [ 19 ] Solution studies of other 5-coordinate Zinc porphyrins have been reported.