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Cyclophosphamide is in the alkylating agent and nitrogen mustard family of medications. [4] It is believed to work by interfering with the duplication of DNA and the creation of RNA. [4] Cyclophosphamide was approved for medical use in the United States in 1959. [4] It is on the World Health Organization's List of Essential Medicines. [6]
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Mesna, sold under the brand name Mesnex among others, is a medication used in those taking cyclophosphamide or ifosfamide to decrease the risk of bleeding from the bladder. [1] It is used either by mouth or injection into a vein. [1] Common side effects include headache, vomiting, sleepiness, loss of appetite, cough, rash, and joint pain. [1]
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