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Side Effects and Risks of Taking Viagra without ED. ... the researchers found more than 10 percent of men having intimacy with men used sildenafil citrate — and that its use is associated with ...
This story was reviewed by Mike Bohl, MD. In the ‘80s, researchers set out to test a medication called sildenafil citrate for treating high blood pressure and angina (chest pain) from heart disease.
Since 1998, the Pfizer-created drug sildenafil citrate has been a reliable treatment for the management of ED. But the active ingredient began its clinical journey as a medication intended to ...
Sildenafil, sold under the brand name Viagra among others, is a medication used to treat erectile dysfunction and pulmonary arterial hypertension. [ 4 ] [ 8 ] It is also sometimes used off-label for the treatment of certain symptoms in secondary Raynaud's phenomenon . [ 9 ]
Viagra (sildenafil), Cialis (tadalafil), Levitra (vardenafil), Stendra (avanafil) and Caverject (alprostadil) are all FDA-approved for the treatment of ED and safe for most men to use.
Chemical structure of sildenafil (Viagra), the prototypical PDE5 inhibitor. A phosphodiesterase type 5 inhibitor (PDE5 inhibitor) is a vasodilating drug that works by blocking the degradative action of cGMP-specific phosphodiesterase type 5 (PDE5) on cyclic GMP in the smooth muscle cells lining the blood vessels supplying various tissues.
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