Search results
Results From The WOW.Com Content Network
Cyanoacetic acid is prepared by treatment of chloroacetate salts with sodium cyanide followed by acidification. [1] [2] Electrosynthesis by cathodic reduction of carbon dioxide and anodic oxidation of acetonitrile also affords cyanoacetic acid. [3] Cyanoacetic acid is used to do cyanoacetylation, first convenient method described by J. Slätt. [4]
Reaction of the sodium cyanoacetate with ethyl bromide in an aqueous–organic two-phase system in the presence of a phase transfer catalyst. [ 4 ] Oxidation of 3-ethoxypropionitrile, an ether , with oxygen under pressure in the presence of cobalt(II) acetate tetrahydrate as catalyst and N -hydroxyphthalimide as a radical generator.
Reaction with cyanide salts gives cyanoacetate NCCH 2 CO 2 Na. [3] Cyanoacetate is a precursor to malonic acid. Sodium chloroacetate is a common laboratory reagent in organic chemistry as illustrated by many entries in the book series Organic Syntheses. With bifunctional nucleophiles, sodium chloroacetate is a precursor to heterocycles. [4] [5 ...
Ethyl cyanohydroxyiminoacetate (oxyma) is the oxime of ethyl cyanoacetate and finds use as an additive for carbodiimides, such as dicyclohexylcarbodiimide (DCC) in peptide synthesis. It acts as a neutralizing reagent for the basicity or nucleophilicity of the DCC due to its pronounced acidity ( pKa 4.60) and suppresses base catalyzed side ...
This reaction also occurs with fiberglass and carbon fiber. The heat released may cause serious burns [ 34 ] or release irritating white smoke. Material safety data sheets for cyanoacrylate instruct users not to wear cotton (jeans) or wool clothing, especially cotton gloves, when applying or handling cyanoacrylates.
With the Using alkali cyanides such as sodium cyanide and polar solvents, the reaction occurs by an S N 2 mechanism via the more-nucleophilic carbon atom of the cyanide ion. [citation needed] [dubious – discuss] This type of reaction together with dimethyl sulfoxide as a solvent is a convenient method for the synthesis of nitriles. [2]
Sodium lauryl sulfate (SLS) is a common ingredient found in the dental hygiene product, but it can cause rashes, canker sores, swollen gums, and perioral dermatitis — bumps and blisters around ...
In some cases cuprous cyanide is used instead of sodium cyanide. [2] Cyanation of ketones or aldehydes yields the corresponding cyanohydrins, which can be done directly with the cyanide ion (the cyanohydrin reaction) or by using bisulfite, followed by displacement of sulfite: [3] [4] Cyanation of aldehyde with bisulfite