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Rubella infection in pregnancy can result in various outcomes ranging from asymptomatic infection to congenital defects to miscarriage and fetal death. [3] [4] If infection occurs 0–11 weeks after conception, the infant has a 90% risk of being affected. [1] If the infection occurs 12–20 weeks after conception, the risk is 20%.
The other 50% are due to maternal or fetal infections, post-natal infections, viral infections due to rubella or cytomegalovirus, ototoxic drugs, [43] exposure to loud sounds, severe head trauma, and premature births [44]
Rubella, also known as German measles or three-day measles, [6] is an infection caused by the rubella virus. [3] This disease is often mild, with half of people not realizing that they are infected. [1] [7] A rash may start around two weeks after exposure and last for three days. [1] It usually starts on the face and spreads to the rest of the ...
A common condition that results in hearing loss is chronic ear infections. [2] Certain infections during pregnancy, such as cytomegalovirus, syphilis and rubella, may also cause hearing loss in the child. [2] [10] Hearing loss is diagnosed when hearing testing finds that a person is unable to hear 25 decibels in at least one ear. [2]
Pregnant women with Rubella are at risk of having a miscarriage or having a baby born with multiple birth defects due to Congenital rubella syndrome. It affected around 12.5 million people in the US. An estimated 11,000 pregnancies ended in miscarriage or stillbirth , just over 2,000 newborn babies died , and of those that survived around ...
Toxoplasmosis: TORCH infection due to Toxoplasma gondii parasite. Condition is commonly associated with undercooked meat or contact with cat feces. Symptoms of this disease include seizures, hydrocephalus, and chorioretinitis. Cytomegalovirus: viral TORCH infection associated with sensorineural hearing loss, hepatomegaly, and jaundice.
The medical condition of deafblindness occurs in different forms. [3] For some, this condition might happen congenitally from birth as a result of genetic defect, for others it happens suddenly due to a form of illness or accident that results in a modality deprivation of either vision or hearing, or both. [8]
The genome encodes several non-coding RNA structures; among them is the rubella virus 3' cis-acting element, which contains multiple stem-loops, one of which has been found to be essential for viral replication. [12] The only significant region of homology between rubella and the alphaviruses is located at the NH2 terminus of non structural ...