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This category of cysts takes over areas of necrotic tissue in the brain from injuries, diseases, or abnormalities, which occur due to the central nervous system's nonregenerative nature. These cysts can affect all germ layers of the CNS, but are most common in the arachnoid mater , and the ventricular space , which may block CSF pathways.
From their common origin at a joint or tendon, ganglion cysts may form in a wide range of locations. Rarely, intraosseous ganglion cysts occur, sometimes in combination with a cyst in the overlying soft tissue. [6] [16] Rare cases of intramuscular ganglion cysts in the gastrocnemius muscle of the calf have been reported.
Enhancement patterns are highly variable, ranging from minimal to marked, and may be solid, rim, or nodular. Adjacent cord edema and syringomyelia and peritumoral cysts may be present in addition to reactive scoliosis. It is nearly impossible to differentiate ganglioglioma from other more common intramedullary neoplasms based on imaging alone.
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Tarlov cysts are most commonly located in the S1 to S4/S5 region of the spinal canal, but can be found along any region of the spine.They usually form on the extradural components of sacrococcygeal nerve roots at the junction of dorsal root ganglion and posterior nerve roots and arise between the endoneurium and perineurium. [10]
Micrograph of a ganglioneuroma with the characteristic ganglion cells. H&E stain. Pathologically, ganglioneuromas are composed of ganglion cells, Schwann cells and fibrous tissue. [5] Ganglioneuromas are solid, firm tumours that typically are white when seen with the naked eye. [citation needed]
This is why brain tumors are far more common in elderly adults than younger ones and why people with immune system disorders are also most susceptable to developing brain tumors.
The term "ganglion" refers to the peripheral nervous system. [1] However, in the brain (part of the central nervous system), the basal ganglia are a group of nuclei interconnected with the cerebral cortex, thalamus, and brainstem, associated with a variety of functions: motor control, cognition, emotions, and learning. [citation needed]