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CA 15-3, for Carcinoma Antigen 15-3, is a tumor marker for many types of cancer, most notably breast cancer. [1] [2] [3]It is derived from MUC1. [4] CA 15-3 and associated CA 27-29 are different epitopes on the same protein antigen product of the breast cancer-associated MUC1 gene.
CA15-3: breast cancer [9] CA27.29: breast cancer [10] CA19-9: Mainly pancreatic cancer, but also colorectal cancer and other types of gastrointestinal cancer. [11] CA-125: Mainly ovarian cancer, [12] but may also be elevated in for example endometrial cancer, fallopian tube cancer, lung cancer, breast cancer and gastrointestinal cancer. [13 ...
CA 15-3; CA 27-29; CA 242 (tumor marker) CA19-9; Calcitonin; Cancer-associated fibroblast; ... Early prostate cancer antigen-2; Estrogen receptor test; F. Fibrin ...
CA 27.29 (aka BR 27.29) and CA 15-3 measure different epitopes of the same protein antigen product of the MUC1 gene seen in breast cancer. CA 27.29 has enhanced sensitivity and specificity compared to CA 15-3 and is elevated in 30% of patients with low-stage disease and 60 to 70% of patients with advanced-stage breast cancer.
In people who lack Lewis antigen A (a blood type antigen on red blood cells), which is about 10% of the white population, CA19-9 is not produced by any cells, [3] even in those with large tumors. [2] This is because of a deficiency of a fucosyltransferase enzyme that is needed to produce Lewis antigen A .
After more than two years of evading COVID-19, I tested positive at home on a rapid antigen test during the summer of 2022. At first, the line was so faint that it didn't even show up in photos.