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Sebaceous glands are holocrine glands that secrete a viscous, lipid-rich fluid consisting of triglycerides, wax esters, squalene, cholesterol, and cholesterol esters [25–27]. The rate of sebum production is related to the number and size of glands which is under hormonal (androgen) control .
Sweat glands play a regenerative role in skin damage. In second-degree cutaneous burns extending into the reticular dermis, regeneration of the epithelium occurs via skin appendages, including hair follicles, sebaceous glands, and sweat glands.
Sebaceous glands produce an oily substance called sebum and sweat glands produce a watery substance called sweat. Sweat glands have ducts, which are pathways to excrete substances to the surface of your skin. Sebaceous glands secrete sebum through your hair follicles and don’t have ducts.
Sebaceous glands are located in the mid-dermis and almost always develop alongside a hair follicle, with an outlet emptying into the follicular canal. This association is known as the pilosebaceous unit.
Eccrine sweat glands allow for temperature control. When body temperature rises during physical activity, increased ambient temperature, or fever, these glands respond by secreting sweat. This sweat is eventually evaporated from the surface of the skin, effectively cooling down body temperature.