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  2. Systemic lupus erythematosus (lupus) is a chronic (long-lasting) autoimmune disease that can affect many parts of the body. Lupus occurs when the immune system, which normally helps protect the body from infection and disease, attacks its own tissues. This attack causes inflammation, and in some cases permanent tissue damage, which can be ...

  3. Systemic Lupus Erythematosus (Lupus) Basics - National Institute...

    www.niams.nih.gov/health-topics/lupus/basics/symptoms-causes

    Systemic lupus erythematosus (lupus) is a chronic (long-lasting) autoimmune disease that can affect many parts of the body. Anyone can get lupus; however, women get the disease more often than men do. It is more common in African Americans and people of American Indian and Asian descent than in white people.

  4. Systemic Lupus Erythematosus (Lupus): Diagnosis, Treatment, and...

    www.niams.nih.gov/health-topics/lupus/diagnosis-treatment-and-steps-to-take

    Treatment of Systemic Lupus Erythematosus (Lupus) Doctors treat lupus based on your symptoms. The goal of treatment is to: Manage symptoms. Prevent, limit, and stop flares. Maintain the lowest level of disease activity, and, if possible, achieve complete remission. Prevent or slow organ damage. Improve your quality of life.

  5. Systemic Lupus Erythematosus (Lupus) Basics: Diagnosis,...

    www.niams.nih.gov/health-topics/lupus/basics/diagnosis-treatment-and-steps-to-take

    Living with systemic lupus erythematosus (lupus) Living with lupus can be hard, but a positive outlook is important. You can do several things to help you live with lupus: Learn to recognize the warning signs of a flare so that you and your doctor might reduce or prevent them. Warning signs include: Increased tiredness. Joint swelling. Pain ...

  6. 系統性紅斑狼瘡(狼瘡)是一種慢性(長期)自身免疫性疾病,可影響多個身體部位。. 任何人都可能患上狼瘡;但女性患病的機率要高於男性。. 與白人相比,狼瘡更常見於非洲裔美國人以及美國印第安人和亞裔美國人。. 某些因素可能觸發免疫系統,導致狼瘡 ...

  7. Systemic Lupus Erythematosus (Lupus): Research & Resources

    www.niams.nih.gov/health-topics/lupus/more-info

    Research Progress Related to Systemic Lupus Erythematosus (Lupus) The NIAMS Lupus Clinical Research Program conducts translational and clinical research into the causes, treatment, and prevention of lupus. In addition, the NIAMS funds and supports many researchers at universities and other organizations throughout the country who are studying ...

  8. Accelerating Medicines Partnership® Rheumatoid Arthritis and...

    www.niams.nih.gov/grants-funding/funded-research/accelerating-medicines/RA-SLE

    The Accelerating Medicines Partnership® Rheumatoid Arthritis and Systemic Lupus Erythematosus (AMP® RA/SLE) program launched in 2014 as one of the original components of the Accelerating Medicines Partnership (AMP). AMP RA/SLE, which was managed by the Foundation for the NIH, relied on a nationwide network of research teams that worked ...

  9. Living With Lupus: Health Information Basics for You and Your...

    www.niams.nih.gov/.../understanding-joint-health/living-with-lupus

    Lupus is a chronic (long-lasting) autoimmune disease. This webpage focuses on systemic lupus erythematosus (SLE), the most common form of lupus. Lupus is different for each person and can affect different areas of the body, including: skin; joints; heart; lungs; kidneys; and the brain. If you have lupus, you may have times of more symptoms (flares) and times of feeling better (remission).

  10. Lupus Clinical Trials Unit | NIAMS

    www.niams.nih.gov/labs/hasni-lab

    Systemic lupus erythematosus (SLE) is a disease that affects females nine times more often than males. People with SLE are often treated with cyclophosphamide (CYC). But CYC can damage a woman s ovaries; it may cause infertility. A drug called GnRHa is sometimes given to protect the ovaries during CYC therapy.

  11. Systemic Autoimmunity Branch | NIAMS

    www.niams.nih.gov/labs/kaplan-lab

    Molecular Biology and Biochemistry, Systems Biology. The broad and long-term objectives of the Systemic Autoimmunity Branch are to further the understanding of the pathophysiology and clinical spectrum of systemic autoimmune diseases and to translate this knowledge into better therapies that improve outcomes for patients with these conditions.