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Unlike in Crohn's disease, the gastrointestinal aspects of ulcerative colitis can generally be cured by surgical removal of the large intestine, though extraintestinal symptoms may persist. This procedure is necessary in the event of: exsanguinating hemorrhage , frank perforation, or documented or strongly suspected carcinoma .
Microscopically, ulcerative colitis is restricted to the mucosa (epithelial lining of the gut), while Crohn's disease affects the full thickness of the bowel wall ("transmural lesions"). Lastly, Crohn's disease and ulcerative colitis present with extra-intestinal manifestations (such as liver problems, arthritis, skin manifestations and eye ...
The Crohn's Disease Activity Index (CDAI) is a scoring system to assess the symptoms associated with Crohn's disease. It assigns a score based on eight clinical factors, including overall well-being, frequency of loose stools, abdominal pain, presence of abdominal masses, changes in weight, low hemoglobin levels, and use of opiates for diarrhea ...
Signs and symptoms Crohn's disease Ulcerative colitis Defecation: Often porridge-like, [1] sometimes steatorrhea: Often mucus-like and with blood [1] Tenesmus: Less common [1] More common [1] Fever: Common [1] Indicates severe disease [1] Fistulae: Common [2] Seldom Weight loss: Often: More seldom
Joint symptoms, particularly in Crohn's disease, can manifest before bowel symptoms do. In ulcerative colitis, the time of the initial arthritis attack appears to be unrelated to the length of the colitis. Furthermore, a relapse of peripheral arthritis is often associated with a flare-up of the gut symptoms, primarily in ulcerative colitis. [7]
“Inflammation from ulcerative colitis and Crohn’s disease can lead to disruptive symptoms, including bowel urgency, that can result in decreased health-related quality of life and potentially ...
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