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Children and adults with Down syndrome are at increased risk of epileptic seizures, which occur in 5–10% of children and up to 50% of adults. [9] This includes an increased risk of a specific type of seizure called infantile spasms. [29] Many (15%) who live 40 years or longer develop Alzheimer's disease. [54]
Adults with Down syndrome often develop chronic health problems, such as severe sleep apnea, digestive disorders, thyroid conditions, and obesity. Many develop Alzheimer’s disease in middle age.
This includes a bill 2021 bill that was introduced called "Charlotte Woodward Organ Transplant Discrimination Prevention Act". The Act's intent is to prevent transplant discrimination at the State and Federal level, against people with Down Syndrome. [9] NDSS collaborated with Mattel on their first Barbie doll with Down Syndrome in 2023. [10]
In honor of Down Syndrome Awareness Month, which happens every October, we rounded up some informative facts about the chromosomal condition.
The average IQ of a young adult with Down syndrome is 50, equivalent to the mental age of an 8- or 9-year-old child, but this number varies widely. [3] At the same time, they enjoy a rich social and emotional awareness. [4] Down syndrome is the most common chromosome abnormality in humans, [3] occurring in about one per 1000 babies born each ...
Infantile epileptic spasms syndrome appears in 1% to 5% of infants with Down syndrome. IESS in those with Down syndrome is milder, more responsive to treatment (due to unknown reasons), and less likely to evolve into Lennox-Gastaut syndrome or other forms of epilepsy. [citation needed] A child with Down syndrome presenting with seizures that ...
The onset of seizures is between the ages of 2 and 5 years of age. EEG shows regular and irregular bilaterally synchronous 2- to 3-Hz spike-waves and polyspike patterns with a 4- to 7-Hz background. 84% of affected children show normal development prior to seizures; the remainder show moderate psychomotor retardation mainly affecting speech.
Research of Down syndrome–related genes is based on studying the genes located on chromosome 21. In general, this leads to an overexpression of the genes. [1] [2] Understanding the genes involved may help to target medical treatment to individuals with Down syndrome. It is estimated that chromosome 21 contains 200 to 250 genes. [3]