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Duloxetine is a serotonin–norepinephrine reuptake inhibitor (SNRI). [12] The precise mechanism for its antidepressant and anxiolytic effects is not known. [10] Common side effects include dry mouth, nausea, feeling tired, dizziness, agitation, sexual problems, and increased sweating. [10]
Common SNRIs include Cymbalta (duloxetine), Effexor XR (venlafaxine) and Pristiq (desvenlafaxine). Tricyclic antidepressants (TCAs). Tricyclic antidepressants are older antidepressants that, due ...
After 2 years, duloxetine and venlafaxine were associated with less weight gain than sertraline. However, these estimates have a limited accuracy because of low medication adherence.
Duloxetine has also been associated with cases of liver failure and should not be prescribed to patients with chronic alcohol use or liver disease. Studies have found that Duloxetine can increase liver function tests three times above their upper normal limit. [67] Patients with coronary artery disease should caution the use of SNRIs. [68]
Opt for smoothies or your comfort foods. If you simply aren’t finding comfort in anything, choose high-fiber and high-protein foods that will keep you energized. Make things easier by meal prepping.
A 2009 Advisory Committee to the U.S. Food and Drug Administration found that online anecdotal reports of discontinuation syndrome related to duloxetine included severe symptoms and exceeded prevalence of both paroxetine and venlafaxine reports by over 250% (although acknowledged this may have been influenced by duloxetine being a much newer ...
Duloxetine. Sold under the brand name Cymbalta, duloxetine is an SNRI that’s used to treat generalized anxiety disorder. ... You can learn more about the pros and cons of Seroquel for and ...
After 2–4 weeks the dose can be increased to 100 mg/ daily. [23] In the use of reboxetine for depression, clinical studies have shown that most patients are treated with an initial dose of reboxetine 8 mg/day, most often as a divided dose. Depending upon patient tolerance and need, the dose can be increased up to 10 mg/day.