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Naftifine hydrochloride (brand names include Exoderil and Naftin) is an allylamine antifungal drug for the topical treatment of tinea pedis, tinea cruris, and tinea corporis (topical fungal infections). Naftifine was invented at the Sandoz Research Institute in Vienna, Austria. It was the first successful antifungal medication of the allylamine ...
Toe nails become infected with fungi in the same way as the rest of the foot, typically by being trapped with fungi in the warm, dark, moist inside of a shoe. Fungal infection of the nails is called tinea unguium, and is not included in the medical definition of "athlete's foot", even though toe nails are part of the foot. Fungi are more ...
A benzothiophene ring is a sulfur analogue of the indole ring found in the amino acid tryptophan. Tryptophan is found in the fungal membrane in addition to lipids such as ergosterol. The benzothiophene ring in sertaconazole mimics tryptophan and increases the drugs ability to form pores in the fungal cell membrane.
“Athlete’s foot, also known as tinea pedis, is a fungal infection that affects the skin of the feet,” explains Dr. Mohammad Rimawi, a board-certified podiatrist in New York City. Left ...
Athlete's foot, known medically as tinea pedis, is a common skin infection of the feet caused by a fungus. [2] Signs and symptoms often include itching, scaling, cracking and redness. [3] In rare cases the skin may blister. [6] Athlete's foot fungus may infect any part of the foot, but most often grows between the toes. [3]
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The fungus was first isolated in 1870 from a tinea cruris patient in Germany by Carl Otto Harz, who named it Acrothecium floccosum. [10] Being unaware of Harz's work, Castellani and Sabouraud identified the species again in 1905 and 1907, respectively, and both placed the fungus into the genus Epidermophyton . [ 11 ]