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Levothyroxine, also known as L-thyroxine, is a synthetic form of the thyroid hormone thyroxine (T 4). [5] [8] It is used to treat thyroid hormone deficiency (hypothyroidism), including a severe form known as myxedema coma. [5]
Thyroxine, also known as T 4, is a hormone produced by the thyroid gland.It is the primary form of thyroid hormone found in the blood and acts as a prohormone of the more active thyroid hormone, triiodothyronine (T 3). [1]
Trade name Type Main indications Company Sales (USD millions/year) ∆ vs 2014 1 Adalimumab: Humira Biologic Rheumatoid arthritis: AbbVie Inc. 14,012 1,469 2 Ledipasvir/sofosbuvir: Harvoni Small molecule Hepatitis C: Gilead Sciences: 13,864 11,737 3 Etanercept: Enbrel Biologic Rheumatoid arthritis: Amgen. Pfizer. 8,697 4,009 4 Infliximab ...
Liotrix is a 4:1 mixture of thyroxine (T 4) and triiodothyronine (T 3) made synthetically.It is used to replenish thyroid hormones in thyroid deficiency and hypothyroidism.The only brand of liotrix available in the U.S. is Thyrolar, manufactured by Forest Laboratories.
They recommend levothyroxine as the preferred treatment. Some practitioners refuse to use desiccated thyroid. [9] Each 64.8 mg (one grain) of thyroid extract contains approximately 38 μg and 9 μg of measurable levothyroxine (T4) and liothyronine (T3), respectively. [1] Arguments against desiccated thyroid include:
Liothyronine may be used when there is an impaired conversion of T 4 to T 3 in peripheral tissues. [2] The dose of liothyronine for hypothyroidism is a lower amount than levothyroxine due it being a higher concentrated synthetic medication. [2]